It is crucial to recognise that ending tuberculosis (TB) demands sustained investment and innovative approaches to the diagnosis, treatment, and prevention of the disease. Despite medical advancements, TB still devastates millions globally, with far-reaching health, social and economic consequences. The Sub-Saharan region, which bears a significant burden of the disease, must implement a combination of strategies to end the TB epidemic. “Through strong strategic interventions and investments in sustainable TB programmes, the region can play its role towards ending TB epidemic by 2030,” writes Dr Jumaa Bwika, a consultant physician and assistant professor, head of pulmonology, department of medicine, Aga Khan University (AKU)Medical College, East Africa.