A suspected outbreak of Mpox among children in Khairpur and adjoining areas of Sindh has prompted the provincial health department to seek urgent laboratory support from the Aga Khan University Laboratory in Karachi, bypassing public sector facilities, as at least nine suspected cases have surfaced in the region. In a formal communication issued by the Directorate General Health Services Sindh, the laboratory manager at the Aga Khan University has been asked to facilitate priority testing and confirm suspected Mpox cases reported from Khairpur Provincial authorities are seeking support from the AKU laboratory for rapid and reliable testing in view of the public health importance of the situation.